Both hypersensitivity reactions and AIDS show a wide range of immune dysfunction signs. Hypersensitive reactions include an increase in histamine production, higher IgE levels, and mast cell degranulation. AIDS is distinguished by a reduction in the number of helper T cells, an increase in the number of cytotoxic T cells, and a decrease in the number of B cells. Mast cells and basophils create histamine in response to allergens. Histamine is the cause of many allergic reactions, including itching, swelling, and increased mucus production. IgE is a kind of antibody that is produced in response to allergen exposure (Bharwani et al.,2021). Mast cells are found in almost all bodily tissues and are responsible for a variety of allergic reaction symptoms.
Mast cells degranulate in response to an allergen, releasing their contents, including histamine. Helper T cells are a type of white blood cell that aids in the regulation of immune responses. Cytotoxic T cells are a type of white blood cell that eliminates contaminated cells. B cells are a type of white blood cell that produces antibodies. AIDS is caused by the human immunodeficiency virus (HIV). HIV attacks helper T cells, causing their numbers to decline. As a result, the immune system’s ability to fight infection deteriorates. HIV also increases the amount and frequency of cytotoxic T cells (Abdi, S. 2020). This improves the immune system’s capacity to destroy infected cells. However, the overall effect of HIV on the immune system is to weaken it, making the infected person more susceptible to other infections and diseases that may progress to AIDS.
Anxiety, depression, irritation, insomnia, and tiredness may be experienced by the patient. These symptoms may have an impact on the patient’s daily life and relationships by making him or her feel overwhelmed, burdened, and incapable of coping. Concentration, focus, and work completion may be difficult for the patient. Furthermore, the patient may withdraw from family and friends and struggle to maintain relationships. Physical symptoms such as headaches, stomachaches, and muscle stiffness may also occur in the patient. By causing pain and suffering, these bodily symptoms may further impair the patient’s daily life and relationships (Bharwani et al.,2021). The patient may find it difficult to engage in activities, or he or she may need frequent breaks. Furthermore, the patient may struggle to sustain physical activity levels or may need to change their routine.
Physical symptoms such as headaches, stomachaches, and muscle stiffness may also occur in the patient.
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