Discuss the pathophysiology of wound healing.

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**peer reviewed scholarly sources within the last 5 years, no books please**
A 19-year-old presents with a deep laceration on the left leg. After sutures are placed the patient is discharged.
Discuss the pathophysiology of wound healing.
What is a granuloma and what is its significance?
Discuss graft versus host disease, would this be a concern for the patient? Discuss your answer.